Tanuj Dada, Dr. E-mail: moc. This article has been cited by other articles in PMC. Abstract Glaucoma is an acquired progressive optic neuropathy which is characterized by changes in the optic nerve head and retinal nerve fiber layer RNFL. White-on-white perimetry is the gold standard for the diagnosis of glaucoma. Hence, the measurement of RNFL thickness has come up.
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Tanuj Dada, Dr. E-mail: moc. This article has been cited by other articles in PMC. Abstract Glaucoma is an acquired progressive optic neuropathy which is characterized by changes in the optic nerve head and retinal nerve fiber layer RNFL. White-on-white perimetry is the gold standard for the diagnosis of glaucoma.
Hence, the measurement of RNFL thickness has come up. Optical coherence tomography and scanning laser polarimetry SLP are the techniques that utilize the evaluation of RNFL for the evaluation of glaucoma. We have reviewed the published literature on the use of SLP in glaucoma. This review elucidates the technological principles, recent developments and the role of SLP in the diagnosis and monitoring of glaucomatous optic neuropathy, in the light of scientific evidence so far.
Keywords: Fixed corneal compensation, glaucoma, retinal nerve fiber layer, scanning laser polarimetry Glaucoma is an acquired progressive optic neuropathy characterized by changes in the optic nerve head and retinal nerve fiber layer RNFL. White-on-white perimetry is the gold standard for diagnosis of glaucoma.
Various new technologies are coming up for the early diagnosis of glaucoma. We performed a systemic search of the PubMed using the terms-glaucoma, scanning laser polarimetry SLP , GDx and RNFL to prepare this review, which elucidates the technological principles, recent developments and the role of SLP in the diagnosis and monitoring of glaucomatous optic neuropathy. Optical coherence tomography OCT based on low-coherence interferometry, generates posterior segment thickness measurements with an axial resolution of eight to ten microns while SLP provides RNFL measurements based upon the birefringence of the retinal ganglion cell axons.
Technologic Principle Retinal nerve fiber layer is made of highly ordered parallel axon bundles which contain microtubules, cylindrical intracellular organelles with diameters smaller than the wavelength of light. The paralleled structure of the microtubules is the source of RNFL birefringence that is the splitting of a light wave by a polar material into two components.
This retardation is proportional to the thickness of the RNFL. Compensation of anterior segment birefringence is thus necessary to isolate RNFL birefringence. Scanning laser polarimetry is basically a confocal scanning laser ophthalmoscope with an integrated ellipsometer to measure retardation. It determines the RNFL thickness, point by point in the peripapillary region, by measuring the total retardation in the light reflected from the retina.
Polarized light passes through the eye and is reflected off the retina. These earlier versions of SLP e. However, later it was found that the axis and magnitude are variable for each individual and using a fixed corneal compensation may not adequately account for the aforementioned variables. GDx-VCC measures and individually compensates for anterior segment birefringence, using a nm laser diode.
Scanning laser polarimetry
Yozshur To study the capability of scanning laser polarimetry with variable corneal compensation GDx VCC to detect differences in retinal nerve fiber layer thickness between normal and glaucomatous eyes in a Taiwan Chinese population. Eytan Blumenthal, and is provided to help glaucoma and cataract patients better understand their condition. The ROC-curve comparison was done according to the method proposed by Hanley et al. Are both nerves damaged in that example? Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication. Because the thickness of this layer ranges from microns, depending on the specific location in the retina, and because the layer is completely lucid, the ability to precisely measure this layer is a breakthrough in the diagnosis and monitoring of glaucoma patients. Yes, the top and bottom of the nerve.
GDX GLAUCOMA PDF
Measurement is obtained from a band 1. It projects a polarized beam of a light into the eye. As this light passes through the NFL tissue, it changes and slow. The detectors measure the change and convert it into thickness units that are graphically displayed. The GDx measure modulation around an ellipse just outside the optics disc and ratios of the thickest points either superiorly or inferiorly to the temporal or nasal regions. The field of view is 15 degree and imaging should be performed through undilated pupil.